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Title: A Simple Method to Detect a Single Gene that Determines a Categorical Trait with Incomplete Penetrance
Contributor(s): Kinghorn, B (author)
Publication Date: 2003
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Abstract: This paper presents a simple method to infer mode of inheritance, penetrance values, allele frequency andgenotype probabilities for a putative biallelic gene that affects a trait with all-or-none expression.Penetrance is assumed to be unaffected by other genes. The preliminary analysis tests the method in avariety of scenarios. Results can be unreliable for data generated with overdominance plus partialpenetrance, but otherwise results were good, with mode of inheritance, allele frequency and penetranceestimated close to true values. The method will work for multiple mutually-exclusive phenotypic classes.
Publication Type: Conference Publication
Conference Name: 50 Years of DNA, Melbourne, 7th-11th July, 2003
Conference Details: 50 Years of DNA, Melbourne, 7th-11th July, 2003
Source of Publication: Proceedings of the Association for the Advancement of Animal Breeding and Genetics Conference, Vol.15, p. 103-106
Publisher: AAABG: Association for the Advancement of Animal Breeding and Genetics
Place of Publication: Australia
Field of Research (FOR): 070201 Animal Breeding
Peer Reviewed: Yes
HERDC Category Description: E1 Refereed Scholarly Conference Publication
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