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|Title:||Stereoselective synthesis, natural occurrence and CB₂ receptor binding affinities of alkylamides from herbal medicines such as 'Echinacea' sp.||Contributor(s):||Matovic, N (author); Matthias, A (author); Gertsch, J (author); Raduner, S (author); Bone, Kerry (author); Lehmann, RP (author); DeVoss, JJ (author)||Publication Date:||2007||DOI:||10.1039/b615487e||Handle Link:||https://hdl.handle.net/1959.11/1508||Abstract:||A divergent synthesis of (2E,4E,8E,10E)- and (2E,4E,8E,10Z)-N-isobutyldodeca-2,4,8,10-tetraenamides from pent-4-yn-1-ol allowed identification of the (2E,4E,8E,10Z)-isomer for the first time in Echinacea species. A short, stereoselective synthesis of the (2E,4E,8E,10Z)-isomer is also described which allowed further biological evaluation of this material, and the demonstration that this isomer does not occur in 'Spilanthes mauritiana' as previously reported.||Publication Type:||Journal Article||Source of Publication:||Organic & Biomolecular Chemistry, 5(1), p. 169-174||Publisher:||Royal Society of Chemistry||Place of Publication:||United Kingdom||ISSN:||1477-0520
|Field of Research (FOR):||060199 Biochemistry and Cell Biology not elsewhere classified||Peer Reviewed:||Yes||HERDC Category Description:||C1 Refereed Article in a Scholarly Journal||Statistics to Oct 2018:||Visitors: 321
|Appears in Collections:||Journal Article|
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