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Title: Morphology and morphometry of the caudate lobe of the liver in two populations
Contributor(s): Sagoo, Mandeep Gill (author); Aland, Rachel  (author); Gosden, Edward (author)
Publication Date: 2018
Open Access: Yes
DOI: 10.1007/s12565-016-0365-7Open Access Link
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Abstract: The caudate lobe of the liver has portal blood supply and hepatic vein drainage independent of the remainder of the liver and may be differentially affected in liver pathologies. Ultrasonographic measurement of the caudate lobe can be used to generate hepatic indices that may indicate cirrhosis. This study investigated the relationship of metrics of the caudate lobe and other morphological features of human livers from a northwest Indian Punjabi population (n = 50) and a UK Caucasian population (n = 25), which may affect the calculation of hepatic indices. The width of the right lobe of the liver was significantly smaller, while the anteroposterior diameter of the caudate lobe and both Harbin's Index and the Hess Index scores were significantly larger in NWI livers than in UKC livers. The Hess Index score, in particular, is much larger in the NWI population (265 %, p < 0.005). Two caudate lobe features were significantly different between the two populations - the shape of the caudate lobe and the development of the caudate process. This study shows significant population differences exist in several metrics and morphological features of the liver. These differences may affect the calculation of hepatic indices, resulting in a greater percentage of false positives of cirrhosis in the NWI population. Population-specific data are required to correctly determine normal ranges.
Publication Type: Journal Article
Source of Publication: Anatomical Science International, 93(1), p. 48-57
Publisher: Springer Japan KK
Place of Publication: Japan
ISSN: 1447-073X
Field of Research (FOR): 119999 Medical and Health Sciences not elsewhere classified
Peer Reviewed: Yes
HERDC Category Description: C1 Refereed Article in a Scholarly Journal
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Appears in Collections:Journal Article
School of Rural Medicine

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